Thermo Fisher Scientific RNF182 Polyclonal Antibody
Human RNF182 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot 및 IHC(P) 검증 완료. 항원 친화 크로마토그래피로 정제된 액상 형태. 연구용으로만 사용 가능하며, NF-κB 경로 관련 단백질 분석에 적합.
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Thermo Fisher Scientific RNF182 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RNF182. Recombinant protein control fragment (Product #RP-88711). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646649 |
Product Specific Information
Immunogen sequence:
VLECCHRVCA KCLYKIIDFG DSPQGVIVCP FCRFETCLPD DEVSSLPDDN NILVNLTCGG KGKKCLPENP TELLLTPKRL ASLVSPSHTS SNCLVITIME VQRESSPSLS STPVVEFYRP ASFDSVTTVS HNWTVWNCTS LL
Ortholog sequence identity:
- Mouse: 100%
- Rat: 99%
Target Information
E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway (PubMed:18298843).
Also plays a role in the inhibition of TLR-triggered innate immune response by mediating Lys-48-linked ubiquitination and subsequent degradation of NF-kappa-B component RELA (PubMed:31432514).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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