Thermo Fisher Scientific MEF2B Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Target Information

The myocyte enhancer factor-2 (MEF-2) family of transcription factors associates with co-repressors or co-activators to regulate the development and function of T cells, neuronal cells, and muscle cells. Four family members arise from alternatively spliced transcripts, termed MEF-2A, -2B, -2C, and -2D. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.