Thermo Fisher Scientific Methyl-Histone H4 (Lys20) Monoclonal Antibody (2C12)
Rabbit monoclonal antibody recognizing tri-methylated Histone H4 (Lys20). Validated for IHC (paraffin). High specificity and sensitivity for epigenetic research. Supplied as liquid, 1 mg/mL, stored at -20°C.
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- pk
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Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution
- 1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2C12 |
| Immunogen | Synthetic peptide derived from human Histone H4 (tri methyl K20), around 1–30 aa (tri methyl K20) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher-order structures.
This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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