Thermo Fisher Scientific NOC3L Polyclonal Antibody
Rabbit polyclonal antibody targeting human NOC3L, validated for ICC/IF. Recombinant protein immunogen. Antigen affinity purified, supplied as liquid in PBS with 40% glycerol. Suitable for research use only.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human NOC3L. Recombinant protein control fragment (Product #RP-107299) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664209 |
Product Specific Information
Immunogen sequence:
IQELTIEEHLI ERKKKLQEKK MHIAALASAI LSDPENNIKK LKELRSMLME QDPDVAVTVR KLVIVSLME
Highest antigen sequence identity to the following orthologs:
- Mouse: 87%
- Rat: 84%
Target Information
GADD 153, a growth arrest and DNA damage-inducible gene, encodes a C/EBP-related nuclear protein also known as CHOP-10 or C/EBP zeta. Its expression is induced by various cellular stresses such as nutrient deprivation and metabolic perturbations. GADD 153 functions to block cells in the G1 to S phase during cell cycle progression by dimerizing with other C/EBP proteins, redirecting dimers from classical to nonclassical binding sites. It acts as a negative modulator of C/EBP-like proteins in certain terminally differentiated cells.
GADD 153 belongs to the CBF/MAK21 family, which includes NOC2L, NOC3L, and NOC4L. NOC3L, also known as factor for adipocyte differentiation 24 (Fad24), promotes adipogenesis by controlling DNA replication during early mitotic clonal expansion (MCE).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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