Thermo Fisher Scientific AMPK alpha-2 Polyclonal Antibody
AMPK alpha-2 단백질을 인식하는 Thermo Fisher Scientific의 다클론 항체. 사람, 생쥐, 랫트 반응성 확인. Western blot에 적합하며, 고순도 액상 형태로 제공. 에너지 대사 관련 연구에 활용 가능.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (CPLDALNTTKP) corresponding to the internal amino acids of PRKAA2 (aa 382–392) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10980001 |
Product Specific Information
- Predicted to react with bovine, canine, and porcine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit and non-catalytic beta and gamma subunits.
AMPK is an important energy-sensing enzyme that monitors cellular energy status. Upon metabolic stress, AMPK becomes activated and phosphorylates key enzymes such as acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), regulating fatty acid and cholesterol biosynthesis.
Mouse studies suggest that this subunit may influence insulin sensitivity and myocardial energy homeostasis during ischemia.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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