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ELK Biotechnology IRF-3 (phospho Ser386) rabbit pAb
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IRF-3 (phospho Ser386) rabbit pAb는 인간 IRF-3의 Ser386 인산화 부위를 인식하는 폴리클로날 항체입니다. WB와 IHC에 적합하며, 세포 내 IRF-3 활성화 연구에 활용됩니다. 고순도 IgG 형태로 -20°C에서 1년 보관 가능합니다.
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- pk
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ELK Biotechnology ES5922-100UL IRF-3 (phospho Ser386) rabbit pAb, 100UL pk판매 단위 pk ·
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ELK Biotechnology ES5922-50UL IRF-3 (phospho Ser386) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology IRF-3 (phospho Ser386) rabbit pAb
제품명
IRF-3 (phospho Ser386) rabbit pAb
공급업체
ELK Biotechnology
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | IRF3; Interferon regulatory factor 3; IRF-3 |
| Applications | WB; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human IRF-3 around the phosphorylation site of Ser386. AA range: 352–401 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 48–55 kDa |
| GeneID (Human) | 3661 |
| Human Swiss-Prot No | Q14653 |
| Cellular Localization | Cytoplasm, Nucleus, Mitochondrion. Shuttles between cytoplasmic and nuclear compartments, with export being the prevailing effect (PubMed:10805757). When activated, IRF3 interaction with CREBBP prevents its export to the cytoplasm (PubMed:10805757). Recruited to mitochondria via TOMM70:HSP90AA1 upon Sendai virus infection (PubMed:25609812). |
| Background | This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] |
| Species Reactivity | Human; Rat; Mouse |
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