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ELK Biotechnology PDX-1 rabbit pAb
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ELK Biotechnology PDX-1 rabbit pAb

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PDX-1 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 IHC에 적합합니다. 인간, 마우스, 랫트에 반응하며, 인슐린 유전자 발현 조절 및 췌장 발달 연구에 활용됩니다. -20°C에서 1년 보관 가능합니다.

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pk
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ELK Biotechnology ES5913-100UL PDX-1 rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES5913-50UL PDX-1 rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology PDX-1 rabbit pAb

ELK Biotechnology PDX-1 rabbit pAb

제품 정보

항목 내용
Product name PDX-1 rabbit pAb
Alternative Names PDX1; IPF1; Pancreas/duodenum homeobox protein 1; PDX-1; Glucose-sensitive factor; GSF; Insulin promoter factor 1; IPF-1; Insulin upstream factor 1; IUF-1; Islet/duodenum homeobox-1; IDX-1; Somatostatin-transactivating factor 1; STF-1
Applications WB; IHC
Recommended Dilutions WB 1:500–2000; IHC-p 1:50–300
Immunogen The antiserum was produced against synthesized peptide derived from human PDX1. AA range: 27–76
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 42 kD
GeneID (Human) 3651
Human Swiss-Prot No P52945
Cellular localization Nucleus; Cytoplasm, cytosol
Species Reactivity Human; Mouse; Rat

Background

The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Jul 2008]

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