ELK Biotechnology IGFBP7 rabbit pAb
IGFBP7 단백질을 인식하는 토끼 다클론 항체로, IHC, IF, ELISA에 사용 가능. 인간, 마우스, 랫트 시료에 반응하며, 합성 펩타이드(AA 191-240)를 면역원으로 사용. -20°C에서 1년간 보관 가능.
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제품명
IGFBP7 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | IGFBP7; MAC25; PSF; Insulin-like growth factor-binding protein 7; IBP-7; IGF-binding protein 7; IGFBP-7; IGFBP-rP1; MAC25 protein; PGI2-stimulating factor; Prostacyclin-stimulating factor; Tumor-derived adhesion factor; TAF |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100 - 1/300 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human IBP7 (AA range: 191-240) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Gene ID (Human) | 3490 |
| Human Swiss-Prot No | Q16270 |
| Cellular Localization | Secreted |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity and regulate IGF availability in body fluids and tissues, modulating IGF binding to its receptors.
This protein binds IGF-I and IGF-II with relatively low affinity and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion.
Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011]
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