
ELK Biotechnology CD50 rabbit pAb
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Product name: | CD50 rabbit pAb |
Alternative Names: | ICAM3; Intercellular adhesion molecule 3; ICAM-3; CDw50; ICAM-R; CD antigen CD50 |
Applications: | WB;IF;ELISA |
Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
Immunogen: | The antiserum was produced against synthesized peptide derived from human CD50/ICAM-3. AA range:484-533 |
Storage: | Rabbit |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
Observed Band: | 42-60kD |
GeneID(Human): | 3385 |
Human Swiss-Prot No: | P32942 |
Cellular localization: | Membrane; Single-pass type I membrane protein. |
Background: | The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016], |
Species Reactivity: | Human;Rat;Mouse; |
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