ELK Biotechnology APLP2 (phospho Tyr755) rabbit pAb
APLP2 단백질의 Tyr755 인산화 부위를 인식하는 토끼 폴리클로날 항체. IHC, IF, ELISA에 적합하며, 인간·생쥐·랫트 시료에서 반응. 세포막 및 핵에 위치한 단백질 연구에 활용 가능. -20°C에서 장기 보관 가능.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology APLP2 (phospho Tyr755) rabbit pAb
제품명
APLP2 (phospho Tyr755) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | APLP2; APPL2; Amyloid-like protein 2; APLP-2; APPH; Amyloid protein homolog; CDEI box-binding protein; CDEBP |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100 - 1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human APLP2 around the phosphorylation site of Tyr755 (AA range: 714-763) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 334 |
| Human Swiss-Prot No. | Q06481 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein; Nucleus |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes amyloid precursor-like protein 2 (APLP2), a member of the APP (amyloid precursor protein) family including APP, APLP1, and APLP2. This protein is ubiquitously expressed and contains heparin-, copper-, and zinc-binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. It interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and APP is required to mediate neuromuscular transmission, spatial learning, and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer’s disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
[provided by RefSeq, Aug 2011]
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.