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ELK Biotechnology HSF1 (phospho Ser121) rabbit pAb
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ELK Biotechnology HSF1 (phospho Ser121) rabbit pAb

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HSF1 단백질의 Ser121 인산화 형태를 인식하는 토끼 폴리클로날 항체. WB, IHC, IF, ELISA에 사용 가능. 인간 및 생쥐 반응성. 핵 및 세포질 내 위치 연구에 적합. -20°C에서 1년 보관.

카탈로그번호
ES5779-xxxxx (2개 옵션)
판매단위
pk
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2개 옵션
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ELK Biotechnology ES5779-100UL HSF1 (phospho Ser121) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES5779-50UL HSF1 (phospho Ser121) rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology HSF1 (phospho Ser121) rabbit pAb

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HSF1 (phospho Ser121) rabbit pAb

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ELK Biotechnology


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항목 내용
Alternative Names HSF1; HSTF1; Heat shock factor protein 1; HSF 1; Heat shock transcription factor 1; HSTF 1
Applications WB; IHC; IF; ELISA
Recommended Dilutions Western Blot: 1/500 - 1/2000
Immunohistochemistry: 1/100 - 1/300
ELISA: 1/20000
Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human HSF1 around the phosphorylation site of Ser121. AA range: 87–136
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 50 kD
GeneID (Human) 3297
Human Swiss-Prot No Q00613
Cellular Localization Nucleus; Cytoplasm; Nucleus, nucleoplasm; Cytoplasm, perinuclear region; Cytoplasm, cytoskeleton, spindle pole; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome; Chromosome, centromere, kinetochore. The monomeric form is cytoplasmic in unstressed cells (PubMed:8455624, PubMed:26159920). Predominantly nuclear protein in both unstressed and heat shocked cells (PubMed:10413683, PubMed:10359787). Translocates in the nucleus upon heat shock (PubMed:8455624). Nucleocytoplasmic shuttling protein (PubMed:26159920). Colocalizes with IER5 in the nucleus (PubMed:27354066). Colocalizes with BAG3 to the nucleus upon heat stress (PubMed:8455624, PubMed:26159920). Localizes in subnuclear granules called nuclear stress bodies (nSBs) upon heat shock (PubMed:11447121, PubMed:1151455).
Background Heat shock transcription factor 1 (HSF1) Homo sapiens. The product of this gene is a transcription factor that is rapidly induced after temperature stress and binds heat shock promoter elements (HSE). This protein plays a role in the regulation of lifespan. Expression of this gene is repressed by phosphorylation, which promotes binding by heat shock protein 90. [provided by RefSeq, Aug 2016]
Species Reactivity Human; Mouse

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