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ELK Biotechnology AIRE-1 rabbit pAb
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ELK Biotechnology AIRE-1 rabbit pAb

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AIRE 단백질을 인식하는 토끼 폴리클로날 항체로, WB와 ELISA에 적합합니다. 인간, 랫드, 마우스 시료에 반응하며, 핵 및 세포질에 주로 위치한 AIRE 단백질 연구에 유용합니다. -20°C에서 1년 보관 가능합니다.

판매단위
pk
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ELK Biotechnology ES5772-100UL AIRE-1 rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES5772-50UL AIRE-1 rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology AIRE-1 rabbit pAb

ELK Biotechnology AIRE-1 rabbit pAb

제품 정보

항목 내용
Product name AIRE-1 rabbit pAb
Alternative Names AIRE; APECED; Autoimmune regulator; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; APECED protein
Applications WB; ELISA
Recommended Dilutions Western Blot: 1/500 - 1/2000
ELISA: 1/5000
Not yet tested in other applications
Immunogen The antiserum was produced against synthesized peptide derived from human AIRE. AA range: 126-175
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 50 kD
GeneID (Human) 326
Human Swiss-Prot No. O43918
Cellular Localization Nucleus, Cytoplasm. Predominantly nuclear but also cytoplasmic (PubMed:11274163, PubMed:14974083). Found in nuclear body-like structures (dots) and in a filamentous vimentin-like pattern (PubMed:11274163, PubMed:14974083, PubMed:26084028). Associated with tubular structures (PubMed:11274163, PubMed:14974083).
Species Reactivity Human; Rat; Mouse

Background

This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and the negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).
[provided by RefSeq, Jun 2012]

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