ELK Biotechnology Hox-C6 rabbit pAb
Human HOXC6 단백질을 인식하는 rabbit polyclonal antibody로, WB, IHC, IF, ELISA 등에 사용 가능. 고순도 IgG 형태로 1 mg/ml 농도 제공. 핵 내 단백질 검출에 적합하며 -20°C에서 1년간 안정적 보관 가능.
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제품명
Hox-C6 rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | HOXC6; HOX3C; Homeobox protein Hox-C6; Homeobox protein CP25; Homeobox protein HHO.C8; Homeobox protein Hox-3C |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human HOXC6 (AA range: 186-235) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 26 kD |
| GeneID (Human) | 3223 |
| Human Swiss-Prot No | P09630 |
| Cellular Localization | Nucleus |
| Species Reactivity | Human; Mouse |
Background
This gene belongs to the homeobox family, members of which encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC, and HOXD, located on different chromosomes and consisting of 9 to 11 genes arranged in tandem.
HOXC6 is one of several HOXC genes located in a cluster on chromosome 12. Three genes—HOXC5, HOXC4, and HOXC6—share a 5′ non-coding exon. Transcripts may include the shared exon spliced to gene-specific exons or include only gene-specific exons. Alternatively spliced transcript variants encoding different isoforms have been identified for HOXC6. Transcript variant two includes the shared exon, and transcript variant one includes only gene-specific exons.
[Provided by RefSeq, Jul 2008]
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