ELK Biotechnology Annexin II (phospho Ser26) rabbit pAb
Annexin II (phospho Ser26) rabbit polyclonal antibody로, 인산화된 Annexin II 단백질의 Ser26 부위를 인식. WB와 ELISA에 적합하며, 인간, 마우스, 랫트 시료에서 반응. 세포 성장 조절 및 신호전달 연구에 활용 가능.
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Annexin II (phospho Ser26) rabbit pAb
제품 개요
Annexin II (phospho Ser26) rabbit polyclonal antibody는 인산화된 Annexin II 단백질의 Ser26 부위를 특이적으로 인식합니다. Annexin II는 세포 성장 조절 및 신호전달 경로에 관여하는 칼슘 의존성 인지질 결합 단백질로, 다양한 생물학적 연구에 사용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Annexin II (phospho Ser26) rabbit pAb |
| Alternative Names | ANXA2; ANX2; ANX2L4; CAL1H; LPC2D; Annexin A2; Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain; Chromobindin-8; Lipocortin II; Placental anticoagulant protein IV; PAP-IV; Protein I; p36 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized phospho-peptide around the phosphorylation site of human Annexin II (phospho Ser26) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 38 kDa |
| Gene ID (Human) | 302 |
| Human Swiss-Prot No. | P07355 |
| Species Reactivity | Human; Mouse; Rat |
| Cellular Localization | Secreted, extracellular space, extracellular matrix, basement membrane. Melanosome. In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism. |
Background
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor that heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9, and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. (provided by RefSeq, Jul 2008)
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