
ELK Biotechnology Acetyl Histone H2A (K5) rabbit pAb
인간 Histone H2A의 Lys5 아세틸화 부위에 특이적인 rabbit polyclonal antibody. WB, IHC, IF, ELISA에 사용 가능하며 핵 및 염색체에 위치한 H2A 단백질 검출에 적합. 고순도 IgG, 1 mg/ml 농도, -20°C에서 1년 보관.
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제품명
Acetyl Histone H2A (K5) rabbit pAb
공급업체
ELK Biotechnology
제품 개요
이 항체는 인간 Histone H2A의 Lys5 아세틸화 부위를 인식하는 rabbit polyclonal antibody입니다. 염색체 구조 및 핵 내 단백질 연구에 적합하며, 다양한 면역분석 응용에 사용됩니다.
스펙 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | H2AFZ; H2AZ; Histone H2A.Z; H2A/z |
| Applications | IHC; IF; WB; ELISA |
| Recommended Dilutions | WB: 1:500–2000 Immunohistochemistry: 1:100–1:300 ELISA: 1:5000 Other applications: Not yet tested |
| Immunogen | Synthesized peptide derived from human Histone H2A around acetylated Lys5 (AA range: 1–50) |
| Host Species | Rabbit |
| Storage Conditions | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 14 kD |
| GeneID (Human) | 3015 |
| Human Swiss-Prot No. | P0C0S5 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse, Rat |
Background
Histones are basic nuclear proteins that form the nucleosome structure of chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of H2A, H2B, H3, and H4. The chromatin fiber is further compacted through the interaction of linker histone H1 with DNA between nucleosomes to form higher-order structures. This gene encodes a replication-independent member of the histone H2A family, distinct from other family members. Studies in mice indicate that functional H2A is essential for embryonic development, and its absence leads to embryonic lethality. (RefSeq, Jul 2008)
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