ELK Biotechnology Histone H1 (phospho Thr17) rabbit pAb
Histone H1 (phospho Thr17) rabbit polyclonal antibody로 인산화된 Thr17 부위를 특이적으로 인식합니다. WB, IHC, IF, ELISA에 적합하며 인간, 마우스, 원숭이에 반응합니다. 핵 및 염색체에 위치하며 고품질 IgG 형식으로 제공됩니다.
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Histone H1 (phospho Thr17) rabbit pAb
제품 개요
ELK Biotechnology에서 제공하는 Histone H1 (phospho Thr17) rabbit polyclonal antibody는 인간 Histone H1의 Thr17 인산화 부위를 인식하도록 제작되었습니다. 다양한 응용 분야(WB, IHC, IF, ELISA)에 사용할 수 있으며, 고순도 IgG 형식으로 제공됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H1 (phospho Thr17) rabbit pAb |
| Alternative Names | HIST1H1B; H1F5; Histone H1.5; Histone H1a; Histone H1b; Histone H1s-3; HIST1H1D; H1F3; Histone H1.3; Histone H1c; Histone H1s-2; HIST1H1E; H1F4; Histone H1.4; Histone H1b; Histone H1s-4 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 Immunohistochemistry: 1/100–1/300 Immunofluorescence: 1/200–1/1000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human Histone H1 around the phosphorylation site of Thr17 (AA range: 1–50) |
| Host | Rabbit |
| Storage | −20°C (1 year) |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 31 kD |
| GeneID (Human) | 3009 / 3007 / 3008 |
| Human Swiss-Prot No | P16401 / P16402 / P10412 |
| Cellular localization | Nucleus, Chromosome. According to PubMed:15911621, more commonly found in heterochromatin. According to PubMed:10997781, associates with actively transcribed chromatin and not heterochromatin. |
| Species Reactivity | Human; Mouse; Monkey |
Background
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules each of H2A, H2B, H3, and H4 form an octamer around which ~146 bp of DNA is wrapped, creating nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes, aiding in chromatin compaction into higher-order structures. This gene, located on chromosome 6p22–p21.3, is intronless and encodes a replication-dependent histone H1 family member. Transcripts lack polyA tails but contain a palindromic termination element.
[Provided by RefSeq, Aug 2015]
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