ELK Biotechnology GROα rabbit pAb
인간, 생쥐, 랫드 시료에 반응하는 GROα 단백질에 대한 토끼 폴리클로날 항체. IHC, IF, ELISA에 사용 가능하며, 고순도 IgG 형식으로 제공. 염증 및 종양 관련 연구에 적합. -20°C에서 1년 보관 가능.
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ELK Biotechnology GROα rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | GROα rabbit pAb |
| Alternative Names | CXCL1; GRO; GRO1; GROA; MGSA; SCYB1; Growth-regulated alpha protein; C-X-C motif chemokine 1; GRO-alpha(1-73); Melanoma growth stimulatory activity; MGSA; Neutrophil-activating protein 3; NAP-3 |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100 - 1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GROα (AA range: 39–88) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 2919 |
| Human Swiss-Prot No | P09341 |
| Cellular Localization | Secreted |
| Species Reactivity | Human; Mouse; Rat |
Background
This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and acts as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.
[provided by RefSeq, Sep 2014]
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