
ELK Biotechnology GFRα-1 rabbit pAb
GFRα-1 rabbit pAb는 인간, 생쥐, 랫트에 반응하는 폴리클로날 항체로 WB, IHC, IF, ELISA에 사용 가능. 인간 GFRα-1 유래 펩타이드로 제작되어 신경세포 생존 및 분화 연구에 적합. 세포막 및 골지체, 엔도솜 등 다양한 세포 위치에서 발현.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology GFRα-1 rabbit pAb
제품명
GFRα-1 rabbit pAb
공급업체
ELK Biotechnology
제품 개요
GFRα-1 rabbit pAb는 glial cell line-derived neurotrophic factor receptor (GDNFR) 계열 단백질을 인식하는 폴리클로날 항체로, GDNF 및 neurturin 신호 경로 연구에 활용됩니다. 이 항체는 인간 GFRα-1 펩타이드(AA 51–100)를 면역원으로 사용하여 제작되었습니다.
스펙 정보
| 항목 | 내용 |
|---|---|
| Product name | GFRα-1 rabbit pAb |
| Alternative Names | GFRA1; GDNFRA; RETL1; TRNR1; GDNF family receptor alpha-1; GDNF receptor alpha-1; GDNFR-alpha-1; GFR-alpha-1; RET ligand 1; TGF-beta-related neurotrophic factor receptor 1 |
| Applications | IHC; IF; WB; ELISA |
| Recommended Dilutions | WB: 1:500–2000 IHC: 1:100–1:300 ELISA: 1:10000 Other applications: Not yet tested |
| Immunogen | Synthesized peptide derived from human GFRα-1 (AA range: 51–100) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 2674 |
| Human Swiss-Prot No | P56159 |
| Cellular Localization | Cell membrane; Lipid-anchor (GPI-anchor); Golgi apparatus; trans-Golgi network; Endosome; Multivesicular body. Mainly localizes to plasma membrane; shifts to vesicular structures in presence of SORL1. |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are potent neurotrophic factors that play key roles in neuron survival and differentiation. This receptor is a GPI-linked cell surface receptor for both GDNF and NTN and mediates activation of the RET tyrosine kinase receptor. It is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants.
제품 이미지
(이미지 없음)
ELK Biotechnology 상품 둘러보기
전체보기문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.
