ELK Biotechnology PTP22 rabbit pAb
PTP22 단백질에 특이적인 rabbit polyclonal antibody로, WB 및 IHC에 적합합니다. 인간, 마우스, 랫트 시료에서 반응하며 세포질에 위치한 단백질 검출에 사용됩니다. -20°C에서 1년 보관 가능합니다.
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ELK Biotechnology PTP22 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | PTP22 rabbit pAb |
| Alternative Names | PTPN22; PTPN8; Tyrosine-protein phosphatase non-receptor type 22; Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP; Lymphoid phosphatase; LyP; PEST-domain phosphatase; PEP |
| Applications | WB; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300 |
| Immunogen | Synthesized peptide derived from the N-terminal region of human PTP22 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 91 kD |
| Gene ID (Human) | 26191 |
| Human Swiss-Prot No. | Q9Y2R2 |
| Cellular Localization | Cytoplasm |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family.
The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway.
Mutations in this gene may be associated with various autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus, and Graves' disease.
Alternatively spliced transcript variants encoding distinct isoforms have been described.
[provided by RefSeq, Mar 2009]
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