Thermo Fisher Scientific ANXA1/Annexin A1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human Annexin A1, suitable for WB, IHC, and IP applications. Recognizes residues 25–75 of Annexin A1. Unconjugated, liquid form, 1 mg/mL concentration. Recommended storage at 4°C and 1-year shelf life.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:2,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 25 to 75 of human Annexin A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan and Chimpanzee
Target Information
Annexin I belongs to a family of Ca²⁺-dependent phospholipid binding proteins that are preferentially located on the cytosolic face of the plasma membrane. Annexin I has a molecular mass of approximately 40 kDa and exhibits phospholipase A₂ inhibitory activity. Since phospholipase A₂ is required for the biosynthesis of potent inflammatory mediators such as prostaglandins and leukotrienes, Annexin I may possess anti-inflammatory properties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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