Thermo Fisher Scientific GABRA1 Polyclonal Antibody
인간 GABRA1 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot에 최적화된 시약으로 높은 특이성과 재현성을 제공. 항원 친화 크로마토그래피로 정제되어 안정적 액상 형태로 공급. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GABRA1. Recombinant protein control fragment (Product #RP-101777). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641810 |
Product Specific Information
- Immunogen sequence:
KPKKVKDPLI KKNNTYAPTA TSYTPNLARG DPGLATIAKS ATIEPKEVKPE - Highest antigen sequence identity to the following orthologs:
Mouse – 100%, Rat – 100%
Target Information
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing hyperpolarization of the membrane through the opening of a Cl⁻ channel associated with the GABAA receptor (GABAA-R) subtype.
GABAA-Rs are important therapeutic targets for sedative, anxiolytic, and hypnotic agents and are implicated in diseases such as epilepsy, anxiety, depression, and substance abuse.
The GABAA-R is a multimeric subunit complex composed of multiple alpha, beta, and gamma subunits, including splice variants. Coexpression of a gamma-subunit is required for benzodiazepine modulation. Phosphorylation of beta-subunits modulates GABAA-R function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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