Thermo Fisher Scientific GALNT4 Polyclonal Antibody
Rabbit polyclonal antibody targeting human GALNT4 protein. Validated for ICC/IF applications. Supplied unconjugated in liquid form, purified by antigen affinity chromatography. Recommended storage at -20°C for long term stability.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human GALNT4. Recombinant protein control fragment (Product #RP-105670) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664045 |
Product Specific Information
Immunogen sequence:
IRFNSVTELCA EVPEQKNYVG MQNCPKDGFP VPANIIWHFK EDGTIFHPHS GLCLSAYRTP EGRPDVQMRT CDA
Highest antigen sequence identity to the following orthologs:
- Mouse: 86%
- Rat: 38%
Target Information
This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes.
GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins.
They are characterized by:
- N-terminal transmembrane domain
- Stem region
- Lumenal catalytic domain containing GT1 motif and Gal/GalNAc transferase motif
- C-terminal ricin/lectin-like domain
GalNAc-Ts have different but overlapping substrate specificities and expression patterns.
In vitro, the encoded protein can complement other GalNAc-Ts in complete O-glycosylation of mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 molecule.
The coding region of this gene is contained within a single exon.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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