Thermo Fisher Scientific IDH1 Polyclonal Antibody
Thermo Fisher Scientific의 IDH1 Polyclonal Antibody는 인간 및 설치류 반응성을 가진 토끼 유래 IgG 항체입니다. Western blot과 IHC에 사용 가능하며, 합성 펩타이드 면역원으로 제작되었습니다. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공되며 연구용으로 적합합니다.
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Thermo Fisher Scientific IDH1 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1.0 µg/mL
- Immunohistochemistry (IHC): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C terminal region of human IDH1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2689500 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%
Target Information
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses: one utilizes NAD(+) and the other NADP(+) as electron acceptors.
Five isocitrate dehydrogenases have been reported:
- Three NAD(+)-dependent isocitrate dehydrogenases localized to the mitochondrial matrix
- Two NADP(+)-dependent isocitrate dehydrogenases (one mitochondrial, one cytosolic)
The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence and plays a role in NADPH regeneration for intraperoxisomal reductions and cytoplasmic NADPH production.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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