Thermo Fisher Scientific HM13 Polyclonal Antibody
HM13 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간 시료에 반응합니다. 면역세포화학(ICC/IF)에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 완충액(40% glycerol, 0.02% sodium azide) 보존, 4°C 단기 및 -20°C 장기 보관 권장.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human HM13. Recombinant protein control fragment (Product # RP-106681) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664178 |
Product Specific Information
Immunogen sequence:
KGEVTEMFSYE ESNPKDPAAV TESKEGTEAS ASKGLEKKEK
- Highest antigen sequence identity to orthologs: mouse 88%, rat 90%
Target Information
Catalyzes intramembrane proteolysis of signal peptides after cleavage from a preprotein, releasing fragments from the ER membrane into the cytoplasm.
Required for generating lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides.
May play a role in graft rejection and in removal of signal peptides from the hepatitis C virus core protein.
Involved in intramembrane cleavage of PSEN1 and XBP1 isoform 1 in a DERL1/RNF139-dependent manner.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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