Thermo Fisher Scientific Kir6.2 (KCNJ11) Polyclonal Antibody
Human Kir6.2(KCNJ11)에 특이적인 Rabbit Polyclonal Antibody로 IHC(P) 등 다양한 연구용 응용에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 버퍼에 보존. 단기 4°C, 장기 -20°C 보관 권장.
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Thermo Fisher Scientific Kir6.2 (KCNJ11) Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:20–1:50
Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Kir6.2 (KCNJ11). Recombinant protein control fragment (Product #RP-100884). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856693 |
Product Specific Information
Immunogen sequence:
TVKVPTPLCT ARQLDEDHSL LEALTLASAR GPLRKRSVPM AKAKPKFSIS PDSLS
Target Information
This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium increases, the voltage range of channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium. Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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