Thermo Fisher Scientific OSGEP Polyclonal Antibody
Human OSGEP 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot, IHC, ICC/IF 등에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/40% 글리세롤 버퍼에 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human OSGEP. Recombinant protein control fragment (Product #RP-98345). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645094 |
Product Specific Information
Immunogen sequence:
FEGSANKIGV GVVRDGKVLA NPRRTYVTPP GTGFLPGDTA RHHRAVILDL LQEALTESGL TSQDIDCIAY TKGP
Highest antigen sequence identity to the following orthologs:
- Mouse: 93%
- Rat: 93%
Target Information
Osgep (O-sialoglycoprotein endopeptidase), also known as GCPL1, is a 335 amino acid protein that belongs to the peptidase M22 family.
Osgep specifically cleaves the 31-Arg-l-Asp-32 bond in glycophorin A, but does not cleave desialylated glycoproteins, unglycosylated proteins, or glycoproteins that are only N-glycosylated.
Though ubiquitously expressed at low levels, highest levels of Osgep are found in liver, skeletal muscle, and kidney.
OSGEPL1 (also known as Qri7) is a 414 amino acid protein that belongs to the KAE1/YgjD family and exists as three alternatively spliced isoforms.
In tRNAs that have codons beginning with adenine, OSGEPL1 is required for the formation of a threonylcarbamoyl group on adenosine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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