Thermo Fisher Scientific LOXL1 Recombinant Rabbit Monoclonal Antibody (4H3V8)
LOXL1 단백질을 인식하는 토끼 단클론 항체로 Western blot 및 ELISA에 적합. HEK293 세포에서 발현된 재조합 항체이며, Protein A로 정제됨. PBS 기반 저장용액에 50% 글리세롤 포함, -20°C에서 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 4H3V8 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 95–370 of human LOXL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.3 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Immunogen Sequence:
RQAPSLPLPG RVGSDTVRGQ ARHPFGFGQV PDNWREVAVG DSTGMARART SVSQQRHGGS ASSVSASAFA STYRQQPSYP QQFPYPQAPF VSQYENYDPA SRTYDQGFVY YRPAGGGVGA GAAAVASAGV IYPYQPRARY EEYGGGEELP EYPPQGFYPA PERPYVPPPP PPPDGLDRRY SHSLYSEGTP GFEQAYPDPG PEAAQAHGGD PRLGWYPPYA NPPPEAYGPP RALEPPYLPV RSSDTPPPGG ERNGAQQGRL SVGSVYRPNQ NGRGLP
Target Information
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of this family is essential for the biogenesis of connective tissue. It encodes an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus is sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is less conserved and may contribute to roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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