Thermo Fisher Scientific TACC3 Monoclonal Antibody (OTI1E8), TrueMAB
인간 TACC3 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot, IHC, ICC/IF, Flow Cytometry에 사용 가능. TrueMAB 포맷으로 고순도 친화 크로마토그래피 정제. PBS/BSA/glycerol 버퍼에 보존하며 -20°C에서 안정적으로 보관.
- 카탈로그번호
- TA501266x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TACC3 Monoclonal Antibody (OTI1E8), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E8 |
| Immunogen | Full-length human recombinant TACC3 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TACC1 is located on the 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members—TACC1, TACC2, and TACC3—map closely to FGFR1, FGFR2, and FGFR3 genes on chromosomes 4, 8, and 10 respectively. Due to their phylogenetic relationship, TACC and FGFR are proposed to have similar roles in cell growth and differentiation. TACC1 contains a conserved C-terminal region similar to the Drosophila homolog D-TACC, which is necessary for normal spindle function. Mammalian TACC proteins interact with centrosomes and microtubules in a similar manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: TA501266_TACC3_Q9Y6A5-1_House_mouse.svg, TA501266_TACC3_Q9Y6A5-1_House_mouse_PDP.jpeg)
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