Thermo Fisher Scientific HDAC1 Polyclonal Antibody
HDAC1 단백질을 인식하는 염소 폴리클로날 항체로, Western blot 및 ChIP assay에 적합합니다. Human과 Mouse 시료에 반응하며, 0.5 mg/mL 농도의 액상 형태로 제공됩니다. HDAC2와 교차 반응 가능성이 있습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution / Amount |
|---|---|
| Western Blot (WB) | 0.3–1 µg/mL |
| ChIP assay (ChIP) | 2 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-PEDAIPEESGDE |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933514 |
Product Specific Information
- This antibody may cross-react with HDAC2.
- Tested in Peptide ELISA: antibody detection limit dilution 1:1,000.
Target Information
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression.
HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex.
It interacts with retinoblastoma tumor-suppressor protein, forming a complex essential for controlling cell proliferation and differentiation.
Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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