Thermo Fisher Scientific LILRB5 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human LILRB5. Recombinant protein control fragment (Product #RP-90059). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LILRB5,uniProtId:O75023-1,ncbiNodeId:9606,antigenRange:27-119,antigenLength:590,antigenImageFileName:PA5-52906_LILRB5_O75023-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52906_LILRB5_O75023-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643371

Product Specific Information

Immunogen sequence: PKPTLWAEPA SVIARGKPVT LWCQGPLETE EYRLDKEGLP WARKRQNPLE PGAKAKFHIP STVYDSAGRY RCYYETPAGW SEPSDPLELV ATG

Highest antigen sequence identity to the following orthologs: Mouse - 55%, Rat - 56%.

Target Information

This gene is a member of the leukocyte immunoglobulin-likereceptor (LIR) family, which is found in a gene cluster atchromosomal region 19q13.4. The encoded protein belongs to thesubfamily B class of LIR receptors which contain two or fourextracellular immunoglobulin domains, a transmembrane domain, andtwo to four cytoplasmic immunoreceptor tyrosine-based inhibitorymotifs (ITIMs). Several other LIR subfamily B receptors areexpressed on immune cells where they bind to MHC class I moleculeson antigen-presenting cells and inhibit stimulation of an immuneresponse. Multiple transcript variants encoding different isoformshave been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.