Thermo Fisher Scientific Fibulin 1 Polyclonal Antibody
Fibulin 1 단백질을 검출하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC(P), ICC/IF 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. 고순도 Affinity chromatography 정제, 액상 형태로 -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FBLN1 (Accession P23142), corresponding to amino acid residues S316–P366 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853174 |
Product Specific Information
Antibody detects endogenous levels of total FBLN1.
Target Information
Fibulin-1 is a modular glycoprotein component of the elastic extracellular matrix fibers, basement membranes, and blood.
It self-associates and binds to calcium, fibronectin, laminin, nidogen, and fibrinogen.
These interactions contribute to its association with basement membranes, connective tissue, elastic fibers, and fibrin clots.
Fibulin-1 expression is stimulated by estrogen in ovarian cancer cell lines and may serve as an indicator for cancer risk or aggressiveness.
It has also been reported to inhibit cancer cell motility with increasing exposure.
The exact function of Fibulin-1 in the cell remains unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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