Thermo Fisher Scientific PCDHA6 Polyclonal Antibody
PCDHA6 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, ICC/IF, ELISA에 사용 가능. Human, Mouse, Rat에 반응하며, 고순도 Affinity Chromatography 정제. PBS/glycerol buffer에 보관되며 -20°C에서 안정적.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–230 of human PCDHA6 (NP_061732.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.94 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855490 |
Product Specific Information
Immunogen sequence:
MVFTPEDRLG KQCLLLPLLL LAAWKVGSGQ LHYSVPEEAK HGTFVGRIAQ DLGLELAELV PRLFRMASKD REDLLEVNLQ NGILFVNSRI DREELCGRSA ECSIHLEVIV DRPLQVFHVD VEVRDINDNP PLFPVEEQRV LIYESRLPDS VFPLEGASDA DVGSNSILTY KLSSSEYFGL DVKINSDDNK QIGLLLKKSL DREEAPAHNL FLTATDGGKP ELTGTVQLLV
Target Information
The PCDHA6 gene is part of the protocadherin alpha gene cluster on chromosome 5, one of three related clusters with an organization similar to B-cell and T-cell receptor gene clusters.
This cluster includes 15 cadherin superfamily genes (13 highly similar and 2 more distantly related). Each gene has N-terminal variable exons encoding six cadherin ectodomains and shared C-terminal constant exons encoding the cytoplasmic domain.
These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that likely play a key role in establishing and maintaining specific neuronal cell-cell connections in the brain.
Alternative splicing has been observed, and additional variants have been suggested though their full-length forms remain undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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