Thermo Fisher Scientific PSMA8 Monoclonal Antibody (2E3)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

2E3

Immunogen

PSMA8 (NP_653263, 143 a.a. approximately 242 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PSMA8,uniProtId:Q8TAA3-1,ncbiNodeId:9606,antigenRange:143-242,antigenLength:256,antigenImageFileName:H00143471-M03A_PSMA8_Q8TAA3-1_House_mouse.svg,antigenImageFileNamePDP:H00143471-M03A_PSMA8_Q8TAA3-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage buffer

ascites

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: GFDDDGISRL YQTDPSGTYH AWKANAIGRS AKTVREFLEK NYTEDAIASD SEAIKLAIKA LLEVVQSGGR NIELAIIRRN QPLKMFSAKE VELYVTEIEK

Target Information

Component of the spermatoproteasome, a proteasome specifically found in testis that promotes acetylation-dependent degradation of histones, thereby participating actively to the exchange of histones during spermatogenesis. The proteasome is a protein complexe that degrades unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds. Required for 20S core proteasome assembly, essential for the degradation of meiotic proteins RAD51 and RPA1 at late prophase I and the progression of meiosis I during spermatogenesis. Localizes to the synaptonemal complex, a zipper-like structure that holds homologous chromosome pairs in synapsis during meiotic prophase I. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.