Thermo Fisher Scientific Phospho-IKK gamma (Ser376) Polyclonal Antibody
Phospho-IKK gamma (Ser376) 폴리클로날 항체로, 인산화된 IKKγ(Ser376) 단백질을 특이적으로 검출합니다. Western blot, IHC, ICC/IF에 사용 가능하며, 사람과 생쥐 시료에 반응합니다. 고순도 정제 항체로 연구용에 적합합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IKBKG (Accession Q9Y6K9), corresponding to amino acid residues around phosphorylated Ser376. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903023 |
Product Specific Information
This antibody detects endogenous levels of IKK gamma only when phosphorylated at Ser376.
Target Information
IKK gamma is the regulatory subunit of the inhibitor of the kappaB kinase (IKK) complex, which activates NF-kappaB, resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene are associated with incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several immunodeficiencies. Multiple transcript variants encoding different isoforms have been identified. A highly similar pseudogene is located in an adjacent region of the X chromosome.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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