Thermo Fisher Scientific Synapsin 3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Synapsin 3. Recombinant protein control fragment (Product #RP-91528). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Synapsin 3,uniProtId:O14994-1,ncbiNodeId:9606,antigenRange:9-148,antigenLength:580,antigenImageFileName:PA5-56976_Synapsin_3_O14994-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56976_Synapsin_3_O14994-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2648121

Product Specific Information

Immunogen sequence: SDSSFMANLP NGYMTDLQRP DSSTSSPASP AMERRHPQPL AASFSSPGSS LFSSLSSAMK QAPQATSGLM EPPGPSTPIV QRPRILLVID DAHTDWSKYF HGKKVNGEIE IRVEQAEFSE LNLAAYVTGG CMVDMQVVRN

Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.

Target Information

This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene`s localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite direction.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.