Thermo Fisher Scientific Centrin 3 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Recommended positive controls: A549, H1299, HCT-116, Neuro2A, CD830, NIH-3T3, Raw264.7, C2C12, PC-12, Rat-2
• Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (83%), Xenopus laevis (89%), Rhesus Monkey (100%), Bovine (98%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

The protein encoded by this gene contains four EF-hand calcium binding domains and belongs to the centrin protein family. Centrins are evolutionarily conserved proteins similar to the CDC31 protein of S. cerevisiae. Yeast CDC31 is located at the centrosome of interphase and mitotic cells, where it plays a key role in centrosome duplication and separation. Multiple centrins have been identified in mammalian cells, some associated with centrosome fractions. This protein is one of the most abundant centrins associated with the centrosome, suggesting a similar function to its yeast counterpart. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.