Thermo Fisher Scientific MARCKS Polyclonal Antibody
Rabbit polyclonal antibody against human MARCKS protein. Validated for IHC (Paraffin) at 1:200–1:500 dilution. Purified via antigen affinity chromatography. Supplied in PBS with 40% glycerol and 0.02% sodium azide. For research use only.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MARCKS (UniProt ID: P29966-1, antigen range: 1–34, length: 332 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2791961 |
Product Specific Information
Immunogen sequence:
MGAQFSKTAA KGEAAAERPG EAAVASSPSK ANGQ
Target Information
MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and acts as an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and the plasma membrane, leading to its redistribution to the cytoplasm. The protein is involved in cell motility, phagocytosis, membrane trafficking, and mitogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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