Thermo Fisher Scientific MRPL18 Polyclonal Antibody
Thermo Fisher Scientific의 MRPL18 폴리클로날 항체는 인간, 생쥐 및 비인간 영장류 시료에서 MRPL18 단백질 검출용으로 사용됩니다. Western blot 및 Immunocytochemistry에 적합하며, 고순도 친화 크로마토그래피로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5101355
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- pk
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Thermo Fisher Scientific MRPL18 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MRPL18 (Accession Q9H0U6), corresponding to amino acid residues L24–S74 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850791 |
Product Specific Information
Antibody detects endogenous levels of total MRPL18.
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and facilitate protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA composition, opposite to prokaryotic ribosomes. Unlike prokaryotic ribosomes, mammalian mitoribosomes lack a 5S rRNA. The proteins composing mitoribosomes vary significantly among species, making sequence homology recognition difficult. The MRPL18 gene encodes a 39S subunit protein belonging to the L18P ribosomal protein family, with three polymorphic sites, one causing an additional amino acid near the N-terminus.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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