Thermo Fisher Scientific Calpain 9 Polyclonal Antibody
Calpain 9 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS와 50% glycerol buffer에 보관. 인체 Calpain 9 단백질(aa 42-340) 기반 면역원 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Calpain 9 (amino acids 42–340 of target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2903494 |
Target Information
Calpains are a well-conserved family of calcium-dependent cysteine proteases. These proteins are heterodimers composed of an invariant small subunit and variable large subunits. The large subunit contains a cysteine protease domain, and both subunits have calcium-binding domains. Calpains are implicated in neurodegenerative processes, as their activation can be induced by calcium influx and oxidative stress.
Calpain 9 is predominantly expressed in the stomach and small intestine, suggesting specialized digestive functions, and has been associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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