Thermo Fisher Scientific COX5A Monoclonal Antibody (1G10)

Applications and Tested Dilution

Product Specifications

Product Specific Information

Protein sequence:

MLGAALRRCA VAATTRADPR GLLHSARTPG PAVAIQSVRC YSHGSQETDE EFDARWVTYF NKPDIDAWEL RKGINTLVTY DMVPEPKIID AALRACRRLN DFASTVRILE VVKDKAGPHK EIYPYVIQEL RPTLNELGIS TPEELGLDKV

Target Information

Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are less defined but may be involved in regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene, COX5AP1, is located on chromosome 14q22.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.