Thermo Fisher Scientific KANK1 Monoclonal Antibody (1773CT634.49.61)
KANK1 단백질을 인식하는 Mouse monoclonal 항체로, Western blot과 IHC(Paraffin)에 사용 가능. Human 시료에 반응하며 Protein G로 정제됨. 연구용으로 세포골격 및 종양 억제 관련 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:25 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1773CT634.49.61 |
| Immunogen | Recombinant protein of human KANK1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897657 |
Target Information
Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization.
KANK1 (KN motif and ankyrin repeat domain-containing protein 1), also known as ANKRD15, is a 1,352 amino acid protein that contains at least 12 exons and 5 ANK repeats.
It binds to beta-catenin and regulates its subcellular distribution. KANK1 is ubiquitously expressed and localizes to the cytoplasm.
It may function as a tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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