Thermo Fisher Scientific MPRIP Polyclonal Antibody
Rabbit polyclonal antibody targeting human MPRIP protein. Suitable for immunohistochemistry (paraffin) applications. Unconjugated form, 1 mg/mL concentration. For research use only, not for diagnostic or resale purposes.
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- pk
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Thermo Fisher Scientific MPRIP Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human MPRIP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555853 |
Target Information
Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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