Thermo Fisher Scientific JLP Polyclonal Antibody
인간 JLP 단백질을 인식하는 Rabbit Polyclonal 항체로 IHC(P) 및 ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 40% 글리세롤 완충액에 보관. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
- 카탈로그번호
- PA559182
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human JLP. Recombinant protein control fragment (Product #RP-89951). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2642850 |
Product Specific Information
Immunogen sequence:
SGQVDKASLC GSMTSNSSAE TDSLLGGITV VGCSAEGVTG AATSPSTNGA SPVMDKPPEM EAENSEVDEN VPTAEEATEA TEGNAGSAED TVDISQTGVY TEHVFTDPLG VQIPEDLSPV YQSSN
Highest antigen sequence identity to the following orthologs:
- Mouse: 92%
- Rat: 90%
Target Information
This gene encodes an adhesion protein involved in the organization of adherens and tight junctions in epithelial and endothelial cells. It is a calcium-independent cell-cell adhesion molecule belonging to the immunoglobulin superfamily, featuring three extracellular immunoglobulin-like loops, a single transmembrane domain, and a cytoplasmic region. The protein acts as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, as well as pseudorabies virus, mediating viral entry into epithelial and neuronal cells. Mutations in this gene are associated with cleft lip and palate/ectodermal dysplasia 1 syndrome and non-syndromic cleft lip with or without cleft palate. Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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