Thermo Fisher Scientific NTPCR Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:10,000–1:25,000

Product Specifications

Product Specific Information

• Predicted reactivity by homology: Bovine

Target Information

C1orf57 (also known as nucleoside triphosphate phosphohydrolase) belongs to the THEP1 NTPase family. It and its mouse homolog, 2310079N02Rik, are 190 amino acid proteins with nucleotide phosphatase activity toward ATP, GTP, TTP, CTP, and UTP. Acting as a monomer, it also hydrolyzes nucleoside diphosphates with lower efficiency.

The gene encoding C1orf57 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. Chromosome 1 contains approximately 3,000 genes and is associated with numerous diseases, including Hutchinson-Gilford progeria (LMNA gene), familial adenomatous polyposis (MUTYH gene), Stickler syndrome, Parkinson’s disease, Gaucher disease, and Usher syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.