Thermo Fisher Scientific PolH Polyclonal Antibody
Thermo Fisher Scientific의 PolH 폴리클로날 항체는 인간 POLH 단백질을 인식하는 Rabbit IgG 기반 항체입니다. Western blot 및 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용되며 안정적인 액상 형태로 제공됩니다.
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Applications
Western Blot (WB)
- Assay-dependent
Immunoprecipitation (IP)
- 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 640 and 690 of Human polymerase (DNA directed), eta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
The XPA gene encodes a zinc metalloprotein that preferentially binds to DNA damaged by UV radiation and chemical carcinogens and is required for the incision step during nucleotide excision repair.
The XPB and XPD genes encode DNA helicases involved in several DNA metabolic pathways, including DNA repair and transcription.
The XPG gene product is an endonuclease that cuts on the 3' side of a DNA lesion during nucleotide excision repair.
Molecular defects in the XP variant (POLH) group maintain normal excision repair, yet they result in a substantial reduction in the ability to synthesize intact daughter DNA strands during DNA replication following DNA damage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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