Thermo Fisher Scientific A-RAF Monoclonal Antibody (24D1)
A-RAF 단백질을 표적하는 Rabbit 모노클로날 항체(24D1)로, Western blot, IHC, ICC/IF 등 다양한 실험에 적합. 고순도 액상 형태로 제공되며, 1 mg/mL 농도. -20°C 보관, 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 24D1 |
| Immunogen | Recombinant human A-RAF protein (around 150–300aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Target Information
Several serine/threonine protein kinases have been implicated as intermediates in signal transduction pathways, including ERK/MAP kinases, ribosomal S6 kinase (Rsk), and Raf-1. Raf-1 is a cytoplasmic protein with intrinsic serine/threonine activity and is broadly expressed in nearly all tested cell lines. It is the cellular homolog of v-Raf, the transforming gene product of the 3611 strain of murine sarcoma virus.
A-Raf, a second member of the Raf gene family of serine/threonine protein kinases, exhibits substantial homology to Raf-1 within the kinase domain but less homology elsewhere. Expression of A-Raf is found at highest levels in urogenital tissues and kidney, and at lowest levels in brain tissue.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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