Thermo Fisher Scientific CCL3 Polyclonal Antibody

Applications

Tested Dilution

Publications

ELISA (ELISA)

5-10 µg/mL

-

Product Specifications

Host/Isotype

Sheep / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant human MIP-1a if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CCL3 (MIP-1 alpha),uniProtId:P10147-1,ncbiNodeId:9606,antigenRange:27-92,antigenLength:92,antigenImageFileName:PA1-75246_CCL3_MIP-1_alpha_P10147-1_Sheep.svg,antigenImageFileNamePDP:PA1-75246_CCL3_MIP-1_alpha_P10147-1_Sheep_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_1090485

Product Specific Information

PA1-75246 specifically detects MIP-1A.

PA1-75246 has been successfully used in ELISA applications.

The PA1-75246 immunogen is Recombinant MIP-1a.

Target Information

Both MIP-1alpha and MIP-1beta are structurally and functionally related CC chemokines. They participate in host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells (e.g. macrophages, lymphocytes and NK cells). While both MIP-1alpha and MIP-1beta exert similar effects on monocytes, their effect on lymphocytes differ; with MIP-1alpha selectively attracting CD8+ lymphocytes, and MIP-1beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1alpha and MIP-1beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1alpha and MIP-1beta are active on human and murine hematopoietic cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.