Thermo Fisher Scientific SLC6A8 Polyclonal Antibody
SLC6A8 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, ELISA, Flow Cytometry 등에 사용 가능. Human 및 Mouse 반응성. Affinity Chromatography로 정제된 액상형 제품이며, -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Flow Cytometry (Flow) | – | View 1 publication |
| ELISA | 1 µg/mL | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 539–635 of human SLC6A8 (NP_005620.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.26 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855804 |
Product Specific Information
Immunogen sequence:
VVYYEPLVYN NTYVYPWWGE AMGWAFALSS MLCVPLHLLG CLLRAKGTMA ERWQHLTQPI WGLHHLEYRA QDADVRGLTT LTPVSESSKV VVVESVM
Target Information
SLC6A8 (solute carrier family 6 member 8), also known as CT1 (creatine transporter 1), CRT or CRTR, is a 635 amino acid multi-pass plasma membrane protein that belongs to the sodium/neurotransmitter (SNF) family.
It is expressed in multiple tissues including kidney, skeletal muscle, heart, brain, prostate, testis, and colon.
SLC6A8 functions to transport creatine into and out of cells, particularly in brain and muscle tissue.
Defects in the SLC6A8 gene cause cerebral creatine deficiency, associated with X-linked creatine deficiency syndrome, characterized by facial anomalies, seizures, and mental retardation.
Multiple isoforms exist due to alternative splicing.
⚠ WARNING
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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