Thermo Fisher Scientific RPSA Monoclonal Antibody (OTI1G3), TrueMAB
Thermo Fisher Scientific의 RPSA Monoclonal Antibody (OTI1G3)은 인간 RPSA 단백질을 인식하는 마우스 IgG1 단일클론 항체입니다. Western blot 및 IHC(Paraffin)에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 2–295 of human RPSA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They play key roles in cell adhesion, differentiation, migration, signaling, neurite outgrowth, and metastasis. Laminin effects are mediated through cell surface receptors, including integrins and non-integrin laminin-binding proteins.
This gene encodes a high-affinity, non-integrin laminin receptor 1 (67 kD laminin receptor, 37 kD laminin receptor precursor, or p40 ribosome-associated protein). The amino acid sequence is highly conserved across species, indicating its essential biological function. Elevated expression of this receptor has been observed in colon carcinoma and lung cancer cells, correlating with invasive and metastatic phenotypes. Multiple pseudogene copies exist due to retropositional events, and two alternatively spliced transcript variants encode the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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