Thermo Fisher Scientific VMP1 Polyclonal Antibody

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human VMP1 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:VMP1,uniProtId:Q96GC9-1,ncbiNodeId:9606,antigenRange:1-50,antigenLength:406,antigenImageFileName:PA5-66716_VMP1_Q96GC9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-66716_VMP1_Q96GC9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.6 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2664384

Product Specific Information

Immunogen sequence: MAENGKNCDQR RVAMNKEHHN GNFTDPSSVN EKKRREREER QNIVLWRQP

Highest antigen sequence identity to the following orthologs - mouse 84%, rat 88%.

Target Information

VMP1 is a stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis.VMP1 is a transmembrane protein that co-localizes with LC3, a marker of the autophagosomes. It interacts with beclin-1, a mammalian autophagy initiator, through the VMP1-Atg domain, which is essential for autophagosome formation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.