Thermo Fisher Scientific VMP1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human VMP1, suitable for detecting autophagy-related protein expression. Supplied as a liquid, 0.6 mg/mL concentration. Recommended storage at 4°C short term or -20°C long term. For research use only.
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human VMP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664384 |
Product Specific Information
Immunogen sequence:
MAENGKNCDQR RVAMNKEHHN GNFTDPSSVN EKKRREREER QNIVLWRQP
Highest antigen sequence identity to the following orthologs:
- Mouse: 84%
- Rat: 88%
Target Information
VMP1 is a stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. It may be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis.
VMP1 is a transmembrane protein that co-localizes with LC3, a marker of autophagosomes. It interacts with beclin-1, a mammalian autophagy initiator, through the VMP1-Atg domain, which is essential for autophagosome formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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